
Shreya Ghanekar
775
Bold Points1x
Finalist
Shreya Ghanekar
775
Bold Points1x
FinalistBio
Incoming first-year medical student (M1) at The Ohio State University College of Medicine.
Education
Ohio State University-Main Campus
Doctoral degree program (PhD, MD, JD, etc.)Majors:
- Neurobiology and Neurosciences
Ohio State University-Main Campus
Bachelor's degree programMajors:
- Neurobiology and Neurosciences
Olentangy High School
High SchoolMiscellaneous
Desired degree level:
Doctoral degree program (PhD, MD, JD, etc.)
Graduate schools of interest:
Transfer schools of interest:
Majors of interest:
Career
Dream career field:
Medicine
Dream career goals:
Physician
Research
Medical Clinical Sciences/Graduate Medical Studies
The Ohio State University Department of Physical Medicine and Rehabilitation — Clinical Research Aide2024 – 2025Biological and Biomedical Sciences, Other
The Ohio State University James Cancer Center — Undergraduate Research Assistant2022 – 2024
Arts
Buckeye Fusion
DanceBuckeye Fusion | 2022 LEGENDS | [Front Row @Parth ...]2020 – 2023
Public services
Volunteering
BHT AAPIO Free Clinic — Scribe Lead2016 – 2024
Future Interests
Volunteering
Philanthropy
Women’s Health Research & Innovation Scholarship
Women of African-American (AA) ancestry experience more aggressive breast cancers, suffer the highest mortality rates, and are disproportionately affected by triple-negative breast cancer.
When I first learned of this discrepancy, it immediately steered my interest towards the emerging field of precision research to enhance clinical delivery for understudied populations. I started my role as an Undergraduate Research Assistant at The Ohio State University (OSU) Comprehensive Cancer Center. Under the guidance of Dr. Toland, my project focused on using isogenic cell lines from individuals of African and European ancestries to evaluate how different TP53 genotypes, wildtype, R175H knock-in, and knock-out, responded to stressors such as gamma irradiation. Ultimately, the AA cell lines demonstrated resilience under stress, while KO lines showed higher proliferation under baseline conditions- indicating preliminary findings that TP53-mediated DNA damage response may vary significantly by ancestry.
This work reinforced the importance of advancing ancestral-based genome research to better understand clinical outcomes for a broader range of women. During this experience, I co-authored a genome-wide association study published in Cancer Research Communications (DOI: 10.1101/2023.12.06.23299442). Furthermore, I presented my own findings titled Characterizing the Heterogeneity of TP53 Mutations on Tumor Phenotypes in Diverse Cell Lines at four major OSU conferences.
At the same time, I felt compelled to explore an often-overlooked aspect of cancer: post-chemotherapy rehabilitation. As a lifelong dancer, I found a unique way to explore this question through the lens of survivorship and rehabilitation at the OSU Department of Physical Medicine & Rehabilitation. Specifically, Dr. Worthen-Chaudhari’s project aimed to evaluate Adapted Argentine Tango as a novel intervention for women suffering from chemotherapy-induced peripheral neuropathy- a debilitating and often permanent side effect of chemotherapy with limited treatment options.
During this clinical study, I worked directly with breast cancer survivors to deliver dance-based exercises targeting balance, coordination, and postural control. Over the course of the intervention, I observed consistent improvements in patient-reported outcomes such as reduced pain, tingling, and instability, as well as noticeable gains in physical confidence and personal empowerment. Ultimately, our early findings have depicted promising improvements in balance and reduced neuropathic symptoms, reinforcing the potential of dance-based rehabilitation as a non-invasive, accessible treatment option.
Based on this research, I co-presenting the State of the Science: Dance and Neurorehabilitation symposium at the American Congress of Rehabilitation Medicine’s Annual Conference alongside my PI, Dr. Worthen-Chaudhari (https://acrm2024.eventscribe.net/fsPopup.asp?PresenterId=1929864&mode=presenterinfo). Subsequently, my presentation titled Systematic Review of Dance-based Interventions Targeting Upper Extremity Function in Occupational Therapy has been published in the Archives of Physical Medicine and Rehabilitation (DOI:10.1016/j.apmr.2025.01.310).
Furthermore, I’ve authored two first-author manuscripts currently in submission:
- Dance-Based Intervention for Upper Extremity Function: A Systematic Review
- Dance as Physical Medicine for Survivors of Cancer: A Scoping Review
Collectively, both these experiences have solidified my desire to bridge basic science with clinical care, all while keeping women’s health at the forefront of my career. As an incoming first-year medical student at The Ohio State University College of Medicine, I aim to continue this work by integrating translational research and innovation into my future as a physician-scientist. I am particularly driven to contribute to equitable advancements in cancer diagnostics, survivorship care, and non-invasive rehabilitative therapies. With the support of this scholarship, I hope to be better positioned to pursue research, advocacy, and academic opportunities that advance evidence-based care for women from diverse backgrounds, address overseen conditions, and provide equitable treatment options. Women’s health deserves tailored and inclusive solutions, and I will strive to be a part of that transformation both during my medical training and future medical practice.